Is Microneedling with PRF Safe? Everything You Need to Know

Advancements in skincare continue to evolve as more people seek firmer, clearer, and more youthful-looking skin. One such innovation gaining momentum is Microneedling with PRF (Platelet-Rich Fibrin), a non-surgical treatment that merges the benefits of microneedling with your body’s natural growth factors. This combination not only amplifies results but also ensures a natural and biocompatible approach to skin rejuvenation.

At Elevate Aesthetics in Sanford, FL, we specialize in offering this cutting-edge therapy, delivering powerful results in a safe, medically supervised environment. But how safe is it, and what should you expect? Let’s explore everything you need to know.

What Is Microneedling with PRF?

Using instruments such as the Rejuvapen NXT®, collagen induction therapy, commonly called microneedling, creates minute, precise micro-wounds on the skin’s outermost layer. Your body responds to these microscopic pathways by initiating its innate repair mechanisms, which boosts the production of collagen and elastin. This process improves skin tone, texture, and elasticity while targeting acne scars, fine lines, pigmentation, and pore size.

When combined with PRF (Platelet-Rich Fibrin)—a second-generation form of PRP (Platelet-Rich Plasma)—the treatment is taken to the next level. Compared to alternatives, PRF delivers a more concentrated mixture of growth factors and white blood cells while remaining free from additional compounds. This accelerates cellular regeneration, promotes new tissue formation, and enhances the skin’s overall health.

How Safe Is Microneedling with PRF?

Microneedling with PRF is widely considered a safe and low-risk procedure, particularly because it uses your own blood to enhance skin healing. At Elevate Aesthetics, PRF is processed using FDA-cleared equipment, and treatments are performed by a licensed aesthetic nurse practitioner with extensive training.

With PRF being derived from your own body (autologous), there’s practically no possibility of experiencing allergic responses or tissue rejection. The controlled injury from microneedling is superficial and precisely managed to avoid significant side effects. Mild redness, sensitivity, or flaking may occur post-treatment, but these are temporary and resolve within days.

Who Is a Good Candidate?

You may be an ideal candidate for Microneedling with PRF if you:

• Have concerns like acne scars, sun damage, fine lines, or uneven skin texture
• Desire non-surgical skin tightening without downtime
• Are in good health and not currently pregnant or breastfeeding
• Prefer a natural, regenerative approach to skincare
• Are looking for long-term skin health improvements with minimal interventions

This Microneedling treatment benefits every skin type and tone. It yields impressive results for individuals in their 20s and 30s pursuing preventative skin maintenance and those aged 40+ seeking more corrective and restorative care.

Benefits of Microneedling with PRF

Choosing Microneedling with PRF offers a range of clinically proven benefits:

• Boosts collagen production for firmer, younger-looking skin
• Enhances texture and tone while reducing pore size
• Delivers acne scar treatment and reduces hyperpigmentation and sun damage.
• Accelerates tissue healing through PRF skin rejuvenation
• Offers non-surgical skin tightening
• Provides natural, long-lasting results
• Minimal downtime and fast recovery
• Safe, biocompatible, and additive-free treatment
• Effective for face, neck, and décolletage

Treatment Areas and Pricing

Elevate Aesthetics offers flexible treatment options based on your aesthetic goals:

• Face Only: $600 (60 minutes)
• Face & Neck: $700 (90 minutes)
• Face, Neck & Décolletage: $775 (120 minutes)

Each session includes a topical anesthetic for comfort, followed by a small blood draw to prepare the PRF. The Rejuvapen NXT® device is then used to perform microneedling, with PRF applied before and during the process to enhance delivery and outcomes.

What to Expect During and After Treatment

The Procedure

• Numbing Preparation: Before beginning the procedure, we apply a topical anesthetic to the treatment area to ensure your comfort.
• PRF Extraction: The Platelet-Rich Fibrin (PRF) is obtained by drawing a minor blood sample and processing it through centrifugation.
• Topical Application: Once the skin is cleansed, the prepared PRF is applied directly to the targeted area.
• Microneedling Process: Using the Rejuvapen NXT® tool, we create targeted microscopic pathways in your skin that enable deep penetration of the PRF.
• Regenerative Activation: This combination of microneedling and PRF application stimulates collagen production and skin regeneration for optimal results.

Aftercare and Recovery

Recovery is straightforward. Immediately following treatment, you may experience redness and a tight, sunburn-like sensation. Light flaking or peeling may occur within 3–5 days. To ensure proper recovery, refrain from applying cosmetics and skincare formulations for at least 24 hours after your procedure and protect your skin from sun exposure.

How Soon Will I See Results?

While some improvement can be seen within two days of the procedure, the full results of PRF skin rejuvenation typically appear around the four-week mark, as your body naturally regenerates new collagen and skin cells. Results continue to improve with subsequent sessions.

For optimal results, a series of three treatments, spaced about four weeks apart, is usually recommended. After this initial series, yearly maintenance sessions are advised to sustain skin vitality and radiance.

How Long Do the Results Last?

Since this treatment stimulates the production of new tissue rather than relying on topical or temporary fixes, the results of Microneedling with PRF are long-lasting. A healthy lifestyle—including proper skincare, diet, and hydration—can significantly prolong these benefits.

Compared to standalone microneedling or topical anti-aging treatments, PRF-enhanced results tend to be more pronounced and sustained over time.

Why Choose Elevate Aesthetics?

At Elevate Aesthetics, we are committed to combining science-backed technologies with compassionate, individualized care. We use the most advanced microneedling equipment and PRF preparation techniques to ensure you receive the safest and most effective outcomes.

Our licensed aesthetic professionals have deep experience in microneedling benefits, skin healing, and non-surgical treatments, allowing us to craft a plan that aligns with your aesthetic goals—contact us to begin your personalized consultation. We proudly serve clients seeking Microneedling with PRF in Sanford, FL, and are here to guide you toward your best skin yet.

Take the First Step Toward Healthier, Glowing Skin

If you’re looking for a safe, natural, and highly effective way to improve your skin’s texture, tone, and overall health, Microneedling with PRF at Elevate Aesthetics is a proven solution. Whether you’re dealing with acne scars, fine lines, or sun damage, this treatment can help restore your skin’s natural glow.

Ready to begin your transformation? Book your Microneedling with PRF Treatment today.