Kybella vs. Other Non-Surgical Fat Reduction Methods: How It Compares in Terms of Effectiveness and Safety

Kybella vs. Other Non-Surgical Fat Reduction Methods

Kybella is an FDA-approved cosmetic treatment used to treat submental fat, resulting in a reduction in the appearance of a double chin. It is made up of a synthetic version of deoxycholic acid, which is naturally found in the body and aids in the breakdown and absorption of fat. This naturally occurring molecule called deoxycholic acid breaks down fat cells and is then eliminated from the body permanently, making Kybella unique among other non-surgical treatments.

What Advantages Does Kybella Have Over Other Non-Surgical Chin Fat Reduction Procedures?

Kybella is a unique non-surgical fat reduction method specifically targeting submental fat, also known as a double chin. Here’s how Kybella compares to other non-surgical fat reduction methods:


  • CoolSculpting. This non-surgical procedure uses controlled cooling to remove stubborn fat from various areas of the body, including the chin. However, CoolSculpting is not specifically designed to target submental fat like Kybella. Also, while CoolSculpting leads to significant fat reduction, it does not provide permanent results like Kybella.
  • SculpSure. This non-surgical fat reduction method uses laser technology to heat and destroy fat cells. Like CoolSculpting, SculpSure can be used to reduce submental fat, but it is not specifically designed for this area. Like CoolSculpting, SculpSure does not offer permanent fat reduction like Kybella.
  • Belkyra. Similar treatment to Kybella, it also uses deoxycholic acid to destroy submental fat cells. However, Belkyra is unavailable in all countries, including the United States. In countries where it is available, Belkyra and Kybella are considered to be equally effective and safe.


What To Prepare Before A Kybella Treatment?

Before considering Kybella treatment to reduce submental fat or double chin, there are a few important preparations, including:


  • Consultation with a qualified healthcare provider. A consultation with a qualified healthcare provider is a must to determine if an individual is a good candidate for Kybella. They will evaluate the patient’s medical history and the severity of the submental fat to determine if Kybella suits best.
  • Discuss expectations. During the consultation, discuss the expectations and the desired results with Kybella. The healthcare provider will be able to provide realistic expectations for the treatment.
  • Avoid blood-thinning medication. Avoid taking any medication that thins the blood, such as aspirin or ibuprofen, for at least a week before the treatment. This can reduce the risk of bruising and bleeding.
  • Avoid alcohol and smoking. Avoid alcohol and smoking for at least 24 hours before the treatment. This can help reduce inflammation and improve healing.
  • Arrive with a clean face. Arrive at the appointment with a clean face and avoid wearing makeup or skincare products on the treated area. This can help reduce the risk of infection.
  • Plan for downtime. While Kybella is a non-surgical treatment, some patients may experience swelling, bruising, and discomfort after the procedure. Plan for some downtime and avoid strenuous physical activity for a few days.
  • Follow post-treatment instructions. The healthcare provider will provide specific post-treatment instructions, such as managing discomfort, when to resume normal activities, and when to schedule a follow-up appointment. Following these instructions closely is important to ensure the best possible results.

That said, preparing for Kybella treatment involves a combination of proper planning, consultation with a qualified healthcare provider, and following pre- and post-treatment instructions to ensure the best possible outcome.

How Does Kybella Work?

Kybella works by using a synthetic form of deoxycholic acid, a naturally occurring molecule in the body that helps to break down and absorb dietary fat. When injected into the submental fat, Kybella destroys fat cells by disrupting the cell membrane, which causes the cell to break down and be absorbed by the body. Over time, the treated fat cells are naturally eliminated from the body, reducing submental fat or a “double chin.”

Kybella is administered through a series of injections directly into the submental fat area. The number of injections and treatment sessions will depend on the amount of fat that needs to be treated and the patient’s desired results. Typically, patients will require two to four treatment sessions, each spaced about four to six weeks apart.

What Are The Advantages of Kybella?

Kybella has several advantages over other non-surgical chin fat reduction procedures:


  • Precision. Kybella is specifically designed to target the submental fat under the chin, which can be difficult to reduce with exercise and diet alone. This targeted approach ensures that only the unwanted fat is destroyed, leaving the surrounding tissue unharmed.
  • Permanent results. Kybella destroys fat cells permanently, unlike other non-surgical chin fat reduction procedures that only shrink the fat cells. Fat cells cannot regenerate once destroyed, resulting in long-term results.
  • Customizable. The number of Kybella treatments required varies depending on the individual’s specific needs and desired results. The treatment can be customized to the patient’s unique anatomy and goals.
  • Minimal side effects. Kybella is a safe procedure with few side effects. The most common temporary side effects are swelling, bruising, and redness at the injection site.
  • Quick recovery. Patients can typically return to normal activities immediately after a Kybella treatment.

In fact, Kybella is an effective and convenient non-surgical chin fat reduction procedure with a high patient satisfaction rate. Its permanent results, non-invasive nature, and minimal side effects make it a preferred choice for many patients seeking to improve their chin profile without surgery.

How Safe Is Kybella Compared to Other Non-Surgical Fat Reduction Methods?

Kybella is considered a safe and effective non-surgical fat reduction method. However, like all medical procedures, it does carry some risks and potential side effects. Here’s how the safety of Kybella compares to other non-surgical fat reduction methods:


  • CoolSculpting. CoolSculpting is considered a safe procedure, with minimal risks and side effects. The most common side effects are temporary numbness, redness, and swelling at the treatment site. However, there have been some reports of more serious complications, such as nerve damage and paradoxical adipose hyperplasia (an increase in fat cells).
  • SculpSure. SculpSure is also considered a safe procedure, with minimal risks and side effects. The most common side effects are mild pain and discomfort during the treatment, as well as temporary swelling, redness, and bruising at the treatment site.
  • Belkyra. Belkyra, like Kybella, uses deoxycholic acid to destroy fat cells. It is generally considered safe, with risks and side effects similar to Kybella.


It’s important to choose a qualified and experienced practitioner to perform the procedure and follow their aftercare instructions to minimize the risk of complications. Additionally, patients should disclose any medical conditions or medications they are taking that may increase their risk of complications.

The Bottom Line

Kybella is an FDA-approved non-surgical treatment specifically designed for the submental area, making it an ideal option for patients seeking to reduce excess fat. My Aesthetic Studio offers Kybella, a non-surgical option to treat double chin and permanently destroy fat cells, which are then gradually eliminated by the body’s natural processes. Ultimately, it’s a permanent solution for submental fat reduction and is a popular and effective option for those seeking to improve their appearance and boost their confidence.


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